BDBM50302048 5-(5-((dimethylamino)methyl)benzofuran-2-yl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL571784

SMILES: CN(C)Cc1ccc2oc(cc2c1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C

InChI Key: InChIKey=SPKAGPPMKYJUPF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50302048 (5-(5-((dimethylamino)methyl)benzofuran-2-yl)-4-(4-...) Show SMILES CN(C)Cc1ccc2oc(cc2c1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C26H23N5O/c1-16-20-8-9-29-23(20)6-5-22(16)30-26-19(12-27)13-28-14-21(26)25-11-18-10-17(15-31(2)3)4-7-24(18)32-25/h4-11,13-14,29H,15H2,1-3H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta by IMAP fluorescence polarization technology				Bioorg Med Chem Lett 19: 5799-802 (2009) Article DOI: 10.1016/j.bmcl.2009.07.113 BindingDB Entry DOI: 10.7270/Q2QR4Z2Q
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50302048 (5-(5-((dimethylamino)methyl)benzofuran-2-yl)-4-(4-...) Show SMILES CN(C)Cc1ccc2oc(cc2c1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C26H23N5O/c1-16-20-8-9-29-23(20)6-5-22(16)30-26-19(12-27)13-28-14-21(26)25-11-18-10-17(15-31(2)3)4-7-24(18)32-25/h4-11,13-14,29H,15H2,1-3H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP fluorescence polarization technology				Bioorg Med Chem Lett 19: 5799-802 (2009) Article DOI: 10.1016/j.bmcl.2009.07.113 BindingDB Entry DOI: 10.7270/Q2QR4Z2Q
					More data for this Ligand-Target Pair