BDBM50302049 4-(4-methyl-1H-indol-5-ylamino)-5-(5-(pyrrolidin-1-ylmethyl)benzofuran-2-yl)nicotinonitrile::CHEMBL569796
SMILES: Cc1c(Nc2c(cncc2-c2cc3cc(CN4CCCC4)ccc3o2)C#N)ccc2[nH]ccc12
InChI Key: InChIKey=USYSUTGHQKSLCI-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50302049 (4-(4-methyl-1H-indol-5-ylamino)-5-(5-(pyrrolidin-1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of PKCdelta by IMAP fluorescence polarization technology | Bioorg Med Chem Lett 19: 5799-802 (2009) Article DOI: 10.1016/j.bmcl.2009.07.113 BindingDB Entry DOI: 10.7270/Q2QR4Z2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50302049 (4-(4-methyl-1H-indol-5-ylamino)-5-(5-(pyrrolidin-1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human PKCtheta by IMAP fluorescence polarization technology | Bioorg Med Chem Lett 19: 5799-802 (2009) Article DOI: 10.1016/j.bmcl.2009.07.113 BindingDB Entry DOI: 10.7270/Q2QR4Z2Q | |||||||||||
More data for this Ligand-Target Pair |