null

SMILES: [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6]-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-[#8])-[#7]-[#6]-1=O

InChI Key: InChIKey=CGGSYGIUDPYWMV-VMXMFDLUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50302072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50302072 (2-((3S,6S,9S,13S)-9-(3-guanidinopropyl)-6-(6-(hydr...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6]-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-[#8])-[#7]-[#6]-1=O |r| Show InChI InChI=1S/C28H42N8O9/c29-28(30)31-12-4-6-19-25(42)34-20(5-2-1-3-7-22(38)36-45)26(43)35-21(15-24(40)41)27(44)32-17(14-23(39)33-19)13-16-8-10-18(37)11-9-16/h8-11,17,19-21,37,45H,1-7,12-15H2,(H,32,44)(H,33,39)(H,34,42)(H,35,43)(H,36,38)(H,40,41)(H4,29,30,31)/t17-,19-,20-,21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 after 30 mins by fluorimetric assay				J Med Chem 52: 7836-46 (2009) Article DOI: 10.1021/jm900850t BindingDB Entry DOI: 10.7270/Q2M046DK
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50302072 (2-((3S,6S,9S,13S)-9-(3-guanidinopropyl)-6-(6-(hydr...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6]-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-[#8])-[#7]-[#6]-1=O |r| Show InChI InChI=1S/C28H42N8O9/c29-28(30)31-12-4-6-19-25(42)34-20(5-2-1-3-7-22(38)36-45)26(43)35-21(15-24(40)41)27(44)32-17(14-23(39)33-19)13-16-8-10-18(37)11-9-16/h8-11,17,19-21,37,45H,1-7,12-15H2,(H,32,44)(H,33,39)(H,34,42)(H,35,43)(H,36,38)(H,40,41)(H4,29,30,31)/t17-,19-,20-,21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8 after 30 mins by fluorimetric assay				J Med Chem 52: 7836-46 (2009) Article DOI: 10.1021/jm900850t BindingDB Entry DOI: 10.7270/Q2M046DK
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50302072 (2-((3S,6S,9S,13S)-9-(3-guanidinopropyl)-6-(6-(hydr...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6]-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-[#8])-[#7]-[#6]-1=O |r| Show InChI InChI=1S/C28H42N8O9/c29-28(30)31-12-4-6-19-25(42)34-20(5-2-1-3-7-22(38)36-45)26(43)35-21(15-24(40)41)27(44)32-17(14-23(39)33-19)13-16-8-10-18(37)11-9-16/h8-11,17,19-21,37,45H,1-7,12-15H2,(H,32,44)(H,33,39)(H,34,42)(H,35,43)(H,36,38)(H,40,41)(H4,29,30,31)/t17-,19-,20-,21-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 after 30 mins by fluorimetric assay				J Med Chem 52: 7836-46 (2009) Article DOI: 10.1021/jm900850t BindingDB Entry DOI: 10.7270/Q2M046DK
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50302072 (2-((3S,6S,9S,13S)-9-(3-guanidinopropyl)-6-(6-(hydr...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6]-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-[#8])-[#7]-[#6]-1=O |r| Show InChI InChI=1S/C28H42N8O9/c29-28(30)31-12-4-6-19-25(42)34-20(5-2-1-3-7-22(38)36-45)26(43)35-21(15-24(40)41)27(44)32-17(14-23(39)33-19)13-16-8-10-18(37)11-9-16/h8-11,17,19-21,37,45H,1-7,12-15H2,(H,32,44)(H,33,39)(H,34,42)(H,35,43)(H,36,38)(H,40,41)(H4,29,30,31)/t17-,19-,20-,21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 after 30 mins by fluorimetric assay				J Med Chem 52: 7836-46 (2009) Article DOI: 10.1021/jm900850t BindingDB Entry DOI: 10.7270/Q2M046DK
					More data for this Ligand-Target Pair