BDBM50302233 2-(1-(3,4-dimethoxyphenyl)propyl)-4-(4-((R)-1-phenylethyl)piperazin-1-yl)isoindoline-1,3-dione::CHEMBL565937

SMILES: CCC(N1C(=O)c2cccc(N3CCN(CC3)[C@H](C)c3ccccc3)c2C1=O)c1ccc(OC)c(OC)c1

InChI Key: InChIKey=JGIWRIFEXHLPDP-JGKWMGOWSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50302233 (2-(1-(3,4-dimethoxyphenyl)propyl)-4-(4-((R)-1-phen...) Show SMILES CCC(N1C(=O)c2cccc(N3CCN(CC3)[C@H](C)c3ccccc3)c2C1=O)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C31H35N3O4/c1-5-25(23-14-15-27(37-3)28(20-23)38-4)34-30(35)24-12-9-13-26(29(24)31(34)36)33-18-16-32(17-19-33)21(2)22-10-7-6-8-11-22/h6-15,20-21,25H,5,16-19H2,1-4H3/t21-,25?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]urotensin 2 from urotensin 2 receptor in human RMS13 cells by scintillation proximity assay				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
UTS2R (RAT)	BDBM50302233 (2-(1-(3,4-dimethoxyphenyl)propyl)-4-(4-((R)-1-phen...) Show SMILES CCC(N1C(=O)c2cccc(N3CCN(CC3)[C@H](C)c3ccccc3)c2C1=O)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C31H35N3O4/c1-5-25(23-14-15-27(37-3)28(20-23)38-4)34-30(35)24-12-9-13-26(29(24)31(34)36)33-18-16-32(17-19-33)21(2)22-10-7-6-8-11-22/h6-15,20-21,25H,5,16-19H2,1-4H3/t21-,25?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair