BDBM50302236 CHEMBL569238::N-(2-(3,4-dimethoxyphenyl)-2-(1,3-dioxo-4-(4-((S)-1-phenylethyl)piperazin-1-yl)isoindolin-2-yl)ethyl)thiophene-2-sulfonamide

SMILES: COc1ccc(cc1OC)C(CNS(=O)(=O)c1cccs1)N1C(=O)c2cccc(N3CCN(CC3)[C@@H](C)c3ccccc3)c2C1=O

InChI Key: InChIKey=XXTPMBVPKVOGOB-UHFKCPIBSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50302236 (CHEMBL569238 | N-(2-(3,4-dimethoxyphenyl)-2-(1,3-d...) Show SMILES COc1ccc(cc1OC)C(CNS(=O)(=O)c1cccs1)N1C(=O)c2cccc(N3CCN(CC3)[C@@H](C)c3ccccc3)c2C1=O |r| Show InChI InChI=1S/C34H36N4O6S2/c1-23(24-9-5-4-6-10-24)36-16-18-37(19-17-36)27-12-7-11-26-32(27)34(40)38(33(26)39)28(22-35-46(41,42)31-13-8-20-45-31)25-14-15-29(43-2)30(21-25)44-3/h4-15,20-21,23,28,35H,16-19,22H2,1-3H3/t23-,28?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]urotensin 2 from urotensin 2 receptor in human RMS13 cells by scintillation proximity assay				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
UTS2R (RAT)	BDBM50302236 (CHEMBL569238 | N-(2-(3,4-dimethoxyphenyl)-2-(1,3-d...) Show SMILES COc1ccc(cc1OC)C(CNS(=O)(=O)c1cccs1)N1C(=O)c2cccc(N3CCN(CC3)[C@@H](C)c3ccccc3)c2C1=O |r| Show InChI InChI=1S/C34H36N4O6S2/c1-23(24-9-5-4-6-10-24)36-16-18-37(19-17-36)27-12-7-11-26-32(27)34(40)38(33(26)39)28(22-35-46(41,42)31-13-8-20-45-31)25-14-15-29(43-2)30(21-25)44-3/h4-15,20-21,23,28,35H,16-19,22H2,1-3H3/t23-,28?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair