BDBM50302261 (R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpiperazin-1-yl)-1-oxoisoindolin-2-yl)butyl)-N-methylthiophene-2-sulfonamide::CHEMBL571535

SMILES: CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCN(C)S(=O)(=O)c1cccs1)c1ccc(OC)c(OC)c1

InChI Key: InChIKey=PKYMOQVCDUAWSB-AREMUKBSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50302261 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpipera...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCN(C)S(=O)(=O)c1cccs1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C31H40N4O5S2/c1-5-33-16-18-34(19-17-33)27-10-6-9-24-25(27)22-35(31(24)36)26(23-13-14-28(39-3)29(21-23)40-4)11-7-15-32(2)42(37,38)30-12-8-20-41-30/h6,8-10,12-14,20-21,26H,5,7,11,15-19,22H2,1-4H3/t26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at urotensin 2 receptor in human RMS13 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization aft...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
UTS2R (RAT)	BDBM50302261 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpipera...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCN(C)S(=O)(=O)c1cccs1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C31H40N4O5S2/c1-5-33-16-18-34(19-17-33)27-10-6-9-24-25(27)22-35(31(24)36)26(23-13-14-28(39-3)29(21-23)40-4)11-7-15-32(2)42(37,38)30-12-8-20-41-30/h6,8-10,12-14,20-21,26H,5,7,11,15-19,22H2,1-4H3/t26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair