null

SMILES: Cc1c(CN([C@@H]2CCNC2)S(C)(=O)=O)ccc2cc(F)ccc12

InChI Key: InChIKey=LNIDNIKEDAQTOW-MRXNPFEDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50302326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50302326 ((R)-N-((6-fluoro-1-methylnaphthalen-2-yl)methyl)-N...) Show SMILES Cc1c(CN([C@@H]2CCNC2)S(C)(=O)=O)ccc2cc(F)ccc12 |r| Show InChI InChI=1S/C17H21FN2O2S/c1-12-14(4-3-13-9-15(18)5-6-17(12)13)11-20(23(2,21)22)16-7-8-19-10-16/h3-6,9,16,19H,7-8,10-11H2,1-2H3/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5893-7 (2009) Article DOI: 10.1016/j.bmcl.2009.08.066 BindingDB Entry DOI: 10.7270/Q28915Z6
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50302326 ((R)-N-((6-fluoro-1-methylnaphthalen-2-yl)methyl)-N...) Show SMILES Cc1c(CN([C@@H]2CCNC2)S(C)(=O)=O)ccc2cc(F)ccc12 |r| Show InChI InChI=1S/C17H21FN2O2S/c1-12-14(4-3-13-9-15(18)5-6-17(12)13)11-20(23(2,21)22)16-7-8-19-10-16/h3-6,9,16,19H,7-8,10-11H2,1-2H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation counting				Bioorg Med Chem Lett 19: 5893-7 (2009) Article DOI: 10.1016/j.bmcl.2009.08.066 BindingDB Entry DOI: 10.7270/Q28915Z6
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50302326 ((R)-N-((6-fluoro-1-methylnaphthalen-2-yl)methyl)-N...) Show SMILES Cc1c(CN([C@@H]2CCNC2)S(C)(=O)=O)ccc2cc(F)ccc12 |r| Show InChI InChI=1S/C17H21FN2O2S/c1-12-14(4-3-13-9-15(18)5-6-17(12)13)11-20(23(2,21)22)16-7-8-19-10-16/h3-6,9,16,19H,7-8,10-11H2,1-2H3/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	735	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation counting				Bioorg Med Chem Lett 19: 5893-7 (2009) Article DOI: 10.1016/j.bmcl.2009.08.066 BindingDB Entry DOI: 10.7270/Q28915Z6
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50302326 ((R)-N-((6-fluoro-1-methylnaphthalen-2-yl)methyl)-N...) Show SMILES Cc1c(CN([C@@H]2CCNC2)S(C)(=O)=O)ccc2cc(F)ccc12 |r| Show InChI InChI=1S/C17H21FN2O2S/c1-12-14(4-3-13-9-15(18)5-6-17(12)13)11-20(23(2,21)22)16-7-8-19-10-16/h3-6,9,16,19H,7-8,10-11H2,1-2H3/t16-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation counting				Bioorg Med Chem Lett 19: 5893-7 (2009) Article DOI: 10.1016/j.bmcl.2009.08.066 BindingDB Entry DOI: 10.7270/Q28915Z6
					More data for this Ligand-Target Pair