BDBM50302427 2-(6-(cyclopropylmethoxy)-9-(2-hydroxy-2-methylpropyl)-1H-phenanthro[9,10-d]imidazol-2-yl)isophthalonitrile::CHEMBL585310

SMILES: CC(C)(O)Cc1ccc2c3nc([nH]c3c3ccc(OCC4CC4)cc3c2c1)-c1c(cccc1C#N)C#N

InChI Key: InChIKey=IJUAGNSOAHCCCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50302427 (2-(6-(cyclopropylmethoxy)-9-(2-hydroxy-2-methylpro...) Show SMILES CC(C)(O)Cc1ccc2c3nc([nH]c3c3ccc(OCC4CC4)cc3c2c1)-c1c(cccc1C#N)C#N Show InChI InChI=1S/C31H26N4O2/c1-31(2,36)14-19-8-10-23-25(12-19)26-13-22(37-17-18-6-7-18)9-11-24(26)29-28(23)34-30(35-29)27-20(15-32)4-3-5-21(27)16-33/h3-5,8-13,18,36H,6-7,14,17H2,1-2H3,(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cells				Bioorg Med Chem Lett 19: 5837-41 (2009) Article DOI: 10.1016/j.bmcl.2009.08.085 BindingDB Entry DOI: 10.7270/Q2MG7PKK
					More data for this Ligand-Target Pair