BDBM50302513 4-(1-methyl-1H-indol-5-ylamino)-5-styrylnicotinonitrile::CHEMBL568186
SMILES: Cn1ccc2cc(Nc3c(\C=C\c4ccccc4)cncc3C#N)ccc12
InChI Key: InChIKey=TWSGSMGLEVFTEX-BQYQJAHWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50302513 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein kinase C delta type
(Homo sapiens (Human)) | BDBM50302513
(4-(1-methyl-1H-indol-5-ylamino)-5-styrylnicotinoni...)Show SMILES Cn1ccc2cc(Nc3c(\C=C\c4ccccc4)cncc3C#N)ccc12 Show InChI InChI=1S/C23H18N4/c1-27-12-11-18-13-21(9-10-22(18)27)26-23-19(15-25-16-20(23)14-24)8-7-17-5-3-2-4-6-17/h2-13,15-16H,1H3,(H,25,26)/b8-7+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of PKCdelta by IMAP kinase assay |
Bioorg Med Chem Lett 19: 5829-32 (2009)
Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC |
More data for this Ligand-Target Pair | |
Protein kinase C theta type
(Homo sapiens (Human)) | BDBM50302513
(4-(1-methyl-1H-indol-5-ylamino)-5-styrylnicotinoni...)Show SMILES Cn1ccc2cc(Nc3c(\C=C\c4ccccc4)cncc3C#N)ccc12 Show InChI InChI=1S/C23H18N4/c1-27-12-11-18-13-21(9-10-22(18)27)26-23-19(15-25-16-20(23)14-24)8-7-17-5-3-2-4-6-17/h2-13,15-16H,1H3,(H,25,26)/b8-7+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of human PKCtheta by IMAP kinase assay |
Bioorg Med Chem Lett 19: 5829-32 (2009)
Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC |
More data for this Ligand-Target Pair | |