BDBM50302522 4-((1H-indol-5-yl)(methyl)amino)-5-styrylnicotinonitrile::CHEMBL576233

SMILES: CN(c1ccc2[nH]ccc2c1)c1c(\C=C\c2ccccc2)cncc1C#N

InChI Key: InChIKey=IXCRWOJIHRXWSN-BQYQJAHWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50302522 (4-((1H-indol-5-yl)(methyl)amino)-5-styrylnicotinon...) Show SMILES CN(c1ccc2[nH]ccc2c1)c1c(\C=C\c2ccccc2)cncc1C#N Show InChI InChI=1S/C23H18N4/c1-27(21-9-10-22-18(13-21)11-12-26-22)23-19(15-25-16-20(23)14-24)8-7-17-5-3-2-4-6-17/h2-13,15-16,26H,1H3/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5829-32 (2009) Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50302522 (4-((1H-indol-5-yl)(methyl)amino)-5-styrylnicotinon...) Show SMILES CN(c1ccc2[nH]ccc2c1)c1c(\C=C\c2ccccc2)cncc1C#N Show InChI InChI=1S/C23H18N4/c1-27(21-9-10-22-18(13-21)11-12-26-22)23-19(15-25-16-20(23)14-24)8-7-17-5-3-2-4-6-17/h2-13,15-16,26H,1H3/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5829-32 (2009) Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC
					More data for this Ligand-Target Pair