BDBM50302526 5-(3-methoxystyryl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL567363

SMILES: COc1cccc(\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)c1

InChI Key: InChIKey=JHSOAROIYKSHKX-VOTSOKGWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50302526 (5-(3-methoxystyryl)-4-(4-methyl-1H-indol-5-ylamino...) Show SMILES COc1cccc(\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)c1 Show InChI InChI=1S/C24H20N4O/c1-16-21-10-11-27-23(21)9-8-22(16)28-24-18(14-26-15-19(24)13-25)7-6-17-4-3-5-20(12-17)29-2/h3-12,14-15,27H,1-2H3,(H,26,28)/b7-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5829-32 (2009) Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50302526 (5-(3-methoxystyryl)-4-(4-methyl-1H-indol-5-ylamino...) Show SMILES COc1cccc(\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)c1 Show InChI InChI=1S/C24H20N4O/c1-16-21-10-11-27-23(21)9-8-22(16)28-24-18(14-26-15-19(24)13-25)7-6-17-4-3-5-20(12-17)29-2/h3-12,14-15,27H,1-2H3,(H,26,28)/b7-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5829-32 (2009) Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC
					More data for this Ligand-Target Pair