BindingDB logo
myBDB logout

null

SMILES: CCCC(CCC)Nc1nc(C)nc2n(ncc12)-c1ccc(OC)cc1C

InChI Key: InChIKey=IPTQJKHMFLHOJE-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302573   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50302573
PNG
(CHEMBL569666 | N-(heptan-4-yl)-1-(4-methoxy-2-meth...)
Show SMILES CCCC(CCC)Nc1nc(C)nc2n(ncc12)-c1ccc(OC)cc1C
Show InChI InChI=1S/C21H29N5O/c1-6-8-16(9-7-2)25-20-18-13-22-26(21(18)24-15(4)23-20)19-11-10-17(27-5)12-14(19)3/h10-13,16H,6-9H2,1-5H3,(H,23,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 32n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP production

Bioorg Med Chem Lett 19: 6144-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.016
BindingDB Entry DOI: 10.7270/Q2FT8M46
More data for this
Ligand-Target Pair