BDBM50302599 1-(2,6-dimethoxypyridin-3-yl)-N-(2-methoxyethyl)-3,6-dimethyl-N-propyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL568685

SMILES: CCCN(CCOC)c1nc(C)nc2n(nc(C)c12)-c1ccc(OC)nc1OC

InChI Key: InChIKey=OWHJSYBWQUEATK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302599   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50302599 (1-(2,6-dimethoxypyridin-3-yl)-N-(2-methoxyethyl)-3...) Show SMILES CCCN(CCOC)c1nc(C)nc2n(nc(C)c12)-c1ccc(OC)nc1OC Show InChI InChI=1S/C20H28N6O3/c1-7-10-25(11-12-27-4)18-17-13(2)24-26(19(17)22-14(3)21-18)15-8-9-16(28-5)23-20(15)29-6/h8-9H,7,10-12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP production				Bioorg Med Chem Lett 19: 6144-7 (2009) Article DOI: 10.1016/j.bmcl.2009.09.016 BindingDB Entry DOI: 10.7270/Q2FT8M46
					More data for this Ligand-Target Pair