BDBM50302605 (2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-methoxy-2-methyltetrahydro-2Hpyran-3,4,5-triol::CHEMBL583016

SMILES: CCOc1ccc(Cc2cc(ccc2Cl)[C@]2(C)OC(OC)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=GLURLYOHPZNJHO-OTGIXZHXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
sodium-dependent glucose cotransporter 2 (SGLT2) (Mus musculus (Mouse))	BDBM50302605 ((2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl...) Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@]2(C)OC(OC)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C22H27ClO6/c1-4-28-16-8-5-13(6-9-16)11-14-12-15(7-10-17(14)23)22(2)20(26)18(24)19(25)21(27-3)29-22/h5-10,12,18-21,24-26H,4,11H2,1-3H3/t18-,19-,20+,21?,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay				J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50302605 ((2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl...) Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@]2(C)OC(OC)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C22H27ClO6/c1-4-28-16-8-5-13(6-9-16)11-14-12-15(7-10-17(14)23)22(2)20(26)18(24)19(25)21(27-3)29-22/h5-10,12,18-21,24-26H,4,11H2,1-3H3/t18-,19-,20+,21?,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptake				J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1
					More data for this Ligand-Target Pair