BDBM50302606 (2S,3R,4R,5R)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phenyl]-5-fluoro-6-methoxy-tetrahydro-pyran-3,4-diol::CHEMBL566940

SMILES: CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(OC)[C@H](F)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=JFVIJDSBSHXAJV-DQKSBWHRSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
sodium-dependent glucose cotransporter 2 (SGLT2) (Mus musculus (Mouse))	BDBM50302606 ((2S,3R,4R,5R)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...) Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(OC)[C@H](F)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C21H24ClFO5/c1-3-27-15-7-4-12(5-8-15)10-14-11-13(6-9-16(14)22)20-19(25)18(24)17(23)21(26-2)28-20/h4-9,11,17-21,24-25H,3,10H2,1-2H3/t17-,18+,19-,20+,21?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay				J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50302606 ((2S,3R,4R,5R)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...) Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(OC)[C@H](F)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C21H24ClFO5/c1-3-27-15-7-4-12(5-8-15)10-14-11-13(6-9-16(14)22)20-19(25)18(24)17(23)21(26-2)28-20/h4-9,11,17-21,24-25H,3,10H2,1-2H3/t17-,18+,19-,20+,21?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptake				J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1
					More data for this Ligand-Target Pair