BDBM50302608 (3S,4R,5R,6S)-2-(benzyloxy)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triol::CHEMBL567778

SMILES: CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(OCc3ccccc3)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=QKEQDXYUUYYDDR-HKQFDGPLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
sodium-dependent glucose cotransporter 2 (SGLT2) (Mus musculus (Mouse))	BDBM50302608 ((3S,4R,5R,6S)-2-(benzyloxy)-6-(4-chloro-3-(4-ethox...) Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(OCc3ccccc3)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C27H29ClO6/c1-2-32-21-11-8-17(9-12-21)14-20-15-19(10-13-22(20)28)26-24(30)23(29)25(31)27(34-26)33-16-18-6-4-3-5-7-18/h3-13,15,23-27,29-31H,2,14,16H2,1H3/t23-,24-,25+,26+,27?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay				J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50302608 ((3S,4R,5R,6S)-2-(benzyloxy)-6-(4-chloro-3-(4-ethox...) Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(OCc3ccccc3)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C27H29ClO6/c1-2-32-21-11-8-17(9-12-21)14-20-15-19(10-13-22(20)28)26-24(30)23(29)25(31)27(34-26)33-16-18-6-4-3-5-7-18/h3-13,15,23-27,29-31H,2,14,16H2,1H3/t23-,24-,25+,26+,27?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptake				J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1
					More data for this Ligand-Target Pair