BDBM50302618 (2S,3R,4R,5S)-2-(4'-Ethoxybiphenyl-4-yl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol::CHEMBL567777

SMILES: CCOc1ccc(cc1)-c1cccc(c1)[C@@H]1OC(OC)[C@@H](O)[C@H](O)[C@H]1O

InChI Key: InChIKey=KQVVKGCCRNPRJA-WYGKVCCSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
sodium-dependent glucose cotransporter 2 (SGLT2) (Mus musculus (Mouse))	BDBM50302618 ((2S,3R,4R,5S)-2-(4'-Ethoxybiphenyl-4-yl)-6-methoxy...) Show SMILES CCOc1ccc(cc1)-c1cccc(c1)[C@@H]1OC(OC)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C20H24O6/c1-3-25-15-9-7-12(8-10-15)13-5-4-6-14(11-13)19-17(22)16(21)18(23)20(24-2)26-19/h4-11,16-23H,3H2,1-2H3/t16-,17-,18+,19+,20?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay				J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50302618 ((2S,3R,4R,5S)-2-(4'-Ethoxybiphenyl-4-yl)-6-methoxy...) Show SMILES CCOc1ccc(cc1)-c1cccc(c1)[C@@H]1OC(OC)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C20H24O6/c1-3-25-15-9-7-12(8-10-15)13-5-4-6-14(11-13)19-17(22)16(21)18(23)20(24-2)26-19/h4-11,16-23H,3H2,1-2H3/t16-,17-,18+,19+,20?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptake				J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1
					More data for this Ligand-Target Pair