BDBM50302620 (2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxyphenoxy)phenyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol::CHEMBL567373

SMILES: CCOc1ccc(Oc2cc(ccc2Cl)[C@@H]2OC(OC)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=ZZWKQTNFWCJGDA-WYGKVCCSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50302620 ((2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxyphenoxy)pheny...) Show SMILES CCOc1ccc(Oc2cc(ccc2Cl)[C@@H]2OC(OC)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C20H23ClO7/c1-3-26-12-5-7-13(8-6-12)27-15-10-11(4-9-14(15)21)19-17(23)16(22)18(24)20(25-2)28-19/h4-10,16-20,22-24H,3H2,1-2H3/t16-,17-,18+,19+,20?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptake				J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1
					More data for this Ligand-Target Pair
sodium-dependent glucose cotransporter 2 (SGLT2) (Mus musculus (Mouse))	BDBM50302620 ((2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxyphenoxy)pheny...) Show SMILES CCOc1ccc(Oc2cc(ccc2Cl)[C@@H]2OC(OC)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C20H23ClO7/c1-3-26-12-5-7-13(8-6-12)27-15-10-11(4-9-14(15)21)19-17(23)16(22)18(24)20(25-2)28-19/h4-10,16-20,22-24H,3H2,1-2H3/t16-,17-,18+,19+,20?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay				J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1
					More data for this Ligand-Target Pair