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BDBM50302823 2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylcarbamoyl)phenoxy)-3-ethoxyphenyl)acetic acid::CHEMBL569719

SMILES: CCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OCC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1

InChI Key: InChIKey=ZICXFSRKEBMUAN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302823   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostanoid DP receptor


(Homo sapiens (Human))
BDBM50302823
PNG
(2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...)
Show SMILES CCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OCC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1
Show InChI InChI=1S/C25H24Cl2N2O7S/c1-3-28-25(32)16-6-9-20(36-21-8-5-15(12-24(30)31)11-22(21)35-4-2)19(13-16)29-37(33,34)23-10-7-17(26)14-18(23)27/h5-11,13-14,29H,3-4,12H2,1-2H3,(H,28,32)(H,30,31)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.91E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from human DP receptor expressed in HEK 293 cells in presence of 0.5% BSA by scintillation counting


Bioorg Med Chem Lett 19: 6419-23 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.052
BindingDB Entry DOI: 10.7270/Q25Q4X20
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50302823
PNG
(2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...)
Show SMILES CCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OCC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1
Show InChI InChI=1S/C25H24Cl2N2O7S/c1-3-28-25(32)16-6-9-20(36-21-8-5-15(12-24(30)31)11-22(21)35-4-2)19(13-16)29-37(33,34)23-10-7-17(26)14-18(23)27/h5-11,13-14,29H,3-4,12H2,1-2H3,(H,28,32)(H,30,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from human CRTH2 expressed in HEK 293 cells in presence of 0.5% BSA by scintillation counting


Bioorg Med Chem Lett 19: 6419-23 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.052
BindingDB Entry DOI: 10.7270/Q25Q4X20
More data for this
Ligand-Target Pair