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BDBM50303000 6-(3,5-dimethylisoxazol-4-yl)-N-(thiophen-2-ylmethyl)quinazolin-4-amine::CHEMBL568379

SMILES: Cc1noc(C)c1-c1ccc2ncnc(NCc3cccs3)c2c1

InChI Key: InChIKey=SFOUDLQYBQLSRX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50303000   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual specificity protein kinase CLK4


(Homo sapiens (Human))
BDBM50303000
PNG
(6-(3,5-dimethylisoxazol-4-yl)-N-(thiophen-2-ylmeth...)
Show SMILES Cc1noc(C)c1-c1ccc2ncnc(NCc3cccs3)c2c1
Show InChI InChI=1S/C18H16N4OS/c1-11-17(12(2)23-22-11)13-5-6-16-15(8-13)18(21-10-20-16)19-9-14-4-3-7-24-14/h3-8,10H,9H2,1-2H3,(H,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 158n/an/an/an/an/an/a



National Human Genome Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Clk4


Bioorg Med Chem Lett 19: 6700-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.121
BindingDB Entry DOI: 10.7270/Q2S46S1C
More data for this
Ligand-Target Pair