null

SMILES: CCn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccccc4F)cc3F)c2s1

InChI Key: InChIKey=NJCUQMYNSWUWGU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50303278 (CHEMBL566836 | N-(4-(2-(1-ethyl-1H-imidazole-4-car...) Show SMILES CCn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccccc4F)cc3F)c2s1 Show InChI InChI=1S/C29H23F2N5O3S/c1-2-36-15-22(33-16-36)25-14-21-26(40-25)24(9-12-32-21)39-23-8-7-17(13-19(23)31)34-27(37)29(10-11-29)28(38)35-20-6-4-3-5-18(20)30/h3-9,12-16H,2,10-11H2,1H3,(H,34,37)(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant VEGFR2 expressed in baculovirus infected Sf9 cells after 10 mins by DELFIA assay				Bioorg Med Chem Lett 19: 6836-9 (2009) Article DOI: 10.1016/j.bmcl.2009.10.095 BindingDB Entry DOI: 10.7270/Q2GM87C1
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50303278 (CHEMBL566836 | N-(4-(2-(1-ethyl-1H-imidazole-4-car...) Show SMILES CCn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccccc4F)cc3F)c2s1 Show InChI InChI=1S/C29H23F2N5O3S/c1-2-36-15-22(33-16-36)25-14-21-26(40-25)24(9-12-32-21)39-23-8-7-17(13-19(23)31)34-27(37)29(10-11-29)28(38)35-20-6-4-3-5-18(20)30/h3-9,12-16H,2,10-11H2,1H3,(H,34,37)(H,35,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of TPR-met autophosphorylation expressed in HEK293T cells after 150 mins by ELISA				Bioorg Med Chem Lett 19: 6836-9 (2009) Article DOI: 10.1016/j.bmcl.2009.10.095 BindingDB Entry DOI: 10.7270/Q2GM87C1
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50303278 (CHEMBL566836 | N-(4-(2-(1-ethyl-1H-imidazole-4-car...) Show SMILES CCn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccccc4F)cc3F)c2s1 Show InChI InChI=1S/C29H23F2N5O3S/c1-2-36-15-22(33-16-36)25-14-21-26(40-25)24(9-12-32-21)39-23-8-7-17(13-19(23)31)34-27(37)29(10-11-29)28(38)35-20-6-4-3-5-18(20)30/h3-9,12-16H,2,10-11H2,1H3,(H,34,37)(H,35,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant C-met expressed in baculovirus infected high five cells after 30 mins by DELFIA assay				Bioorg Med Chem Lett 19: 6836-9 (2009) Article DOI: 10.1016/j.bmcl.2009.10.095 BindingDB Entry DOI: 10.7270/Q2GM87C1
					More data for this Ligand-Target Pair