BDBM50303577 (R)-(1-(2-Morpholinoethyl)-1H-indol-3-yl)(spiro[2.5]octan-1-yl)-methanone::CHEMBL576057

SMILES: O=C(C1CC11CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12

InChI Key: InChIKey=MUBBINBGCICILP-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50303577 ((R)-(1-(2-Morpholinoethyl)-1H-indol-3-yl)(spiro[2....) Show SMILES O=C(C1CC11CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12 Show InChI InChI=1S/C23H30N2O2/c26-22(20-16-23(20)8-4-1-5-9-23)19-17-25(21-7-3-2-6-18(19)21)11-10-24-12-14-27-15-13-24/h2-3,6-7,17,20H,1,4-5,8-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells				J Med Chem 53: 295-315 (2010) Article DOI: 10.1021/jm901214q BindingDB Entry DOI: 10.7270/Q2KD1Z00
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50303577 ((R)-(1-(2-Morpholinoethyl)-1H-indol-3-yl)(spiro[2....) Show SMILES O=C(C1CC11CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12 Show InChI InChI=1S/C23H30N2O2/c26-22(20-16-23(20)8-4-1-5-9-23)19-17-25(21-7-3-2-6-18(19)21)11-10-24-12-14-27-15-13-24/h2-3,6-7,17,20H,1,4-5,8-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells				J Med Chem 53: 295-315 (2010) Article DOI: 10.1021/jm901214q BindingDB Entry DOI: 10.7270/Q2KD1Z00
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50303577 ((R)-(1-(2-Morpholinoethyl)-1H-indol-3-yl)(spiro[2....) Show SMILES O=C(C1CC11CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12 Show InChI InChI=1S/C23H30N2O2/c26-22(20-16-23(20)8-4-1-5-9-23)19-17-25(21-7-3-2-6-18(19)21)11-10-24-12-14-27-15-13-24/h2-3,6-7,17,20H,1,4-5,8-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay				J Med Chem 53: 295-315 (2010) Article DOI: 10.1021/jm901214q BindingDB Entry DOI: 10.7270/Q2KD1Z00
					More data for this Ligand-Target Pair