BDBM50303595 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(quinolin-4-ylamino)phenyl)urea::CHEMBL571544

SMILES: Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cccc(Nc2ccnc3ccccc23)c1)C(C)(C)C

InChI Key: InChIKey=SRNCLFNWGMXJLX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50303595 (1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(q...) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cccc(Nc2ccnc3ccccc23)c1)C(C)(C)C Show InChI InChI=1S/C30H30N6O/c1-20-12-14-23(15-13-20)36-28(19-27(35-36)30(2,3)4)34-29(37)33-22-9-7-8-21(18-22)32-26-16-17-31-25-11-6-5-10-24(25)26/h5-19H,1-4H3,(H,31,32)(H2,33,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Genomics Centre of the Max Planck Society Curated by ChEMBL					Assay Description Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...				J Med Chem 53: 357-67 (2010) Article DOI: 10.1021/jm901297e BindingDB Entry DOI: 10.7270/Q29W0FKC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50303595 (1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(q...) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cccc(Nc2ccnc3ccccc23)c1)C(C)(C)C Show InChI InChI=1S/C30H30N6O/c1-20-12-14-23(15-13-20)36-28(19-27(35-36)30(2,3)4)34-29(37)33-22-9-7-8-21(18-22)32-26-16-17-31-25-11-6-5-10-24(25)26/h5-19H,1-4H3,(H,31,32)(H2,33,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Genomics Centre of the Max Planck Society Curated by ChEMBL					Assay Description Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assay				J Med Chem 53: 357-67 (2010) Article DOI: 10.1021/jm901297e BindingDB Entry DOI: 10.7270/Q29W0FKC
					More data for this Ligand-Target Pair