BDBM50303660 CHEMBL566005::N-{(E)-3-[1-(2,4-Dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}-3,5-difluorobenzenesulfonamide
SMILES: Cc1cn(Cc2ccc(Cl)cc2Cl)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(F)cc(F)c3)cc(F)cc12
InChI Key: InChIKey=UZUFJJXAXDSHIH-HWKANZROSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50303660 (CHEMBL566005 | N-{(E)-3-[1-(2,4-Dichlorobenzyl)-5-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry, Inc. Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting | J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H | |||||||||||
More data for this Ligand-Target Pair |