BDBM50303665 4,5-Dichlorothiophene-2-sulfonic Acid{(E)-3-[1-(3-Cyanobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}amide::CHEMBL566006

SMILES: Cc1cn(Cc2cccc(c2)C#N)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12

InChI Key: InChIKey=LQLVCLIJKSFUPI-AATRIKPKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50303665 (4,5-Dichlorothiophene-2-sulfonic Acid{(E)-3-[1-(3-...) Show SMILES Cc1cn(Cc2cccc(c2)C#N)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12 Show InChI InChI=1S/C24H16Cl2FN3O3S2/c1-14-12-30(13-16-4-2-3-15(7-16)11-28)23-17(8-18(27)9-19(14)23)5-6-21(31)29-35(32,33)22-10-20(25)24(26)34-22/h2-10,12H,13H2,1H3,(H,29,31)/b6-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50303665 (4,5-Dichlorothiophene-2-sulfonic Acid{(E)-3-[1-(3-...) Show SMILES Cc1cn(Cc2cccc(c2)C#N)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12 Show InChI InChI=1S/C24H16Cl2FN3O3S2/c1-14-12-30(13-16-4-2-3-15(7-16)11-28)23-17(8-18(27)9-19(14)23)5-6-21(31)29-35(32,33)22-10-20(25)24(26)34-22/h2-10,12H,13H2,1H3,(H,29,31)/b6-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	466	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serum				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair