null
SMILES: CN1C(=O)C(Cc2ccc3ccccc3c2)c2c1cccc2CCC(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1
InChI Key: InChIKey=GSMAPKFLUHDKRW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human)) | BDBM50303676 (4,5-Dichloro-thiophene-2-sulfonic acid[3-(1-methyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry, Inc. Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting | J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human)) | BDBM50303676 (4,5-Dichloro-thiophene-2-sulfonic acid[3-(1-methyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 635 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry, Inc. Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serum | J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H | |||||||||||
More data for this Ligand-Target Pair |