BDBM50303678 CHEMBL585100::Thiophene-2-sulfonic acid [3-(5-fluoro-3-methyl-1-naphthalen-2-ylmethyl-1H-indol-7-yl)-propionyl]-amide

SMILES: Cc1cn(Cc2ccc3ccccc3c2)c2c(CCC(=O)NS(=O)(=O)c3cccs3)cc(F)cc12

InChI Key: InChIKey=WNXBDBPLFBDSEQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50303678 (CHEMBL585100 | Thiophene-2-sulfonic acid [3-(5-flu...) Show SMILES Cc1cn(Cc2ccc3ccccc3c2)c2c(CCC(=O)NS(=O)(=O)c3cccs3)cc(F)cc12 Show InChI InChI=1S/C27H23FN2O3S2/c1-18-16-30(17-19-8-9-20-5-2-3-6-21(20)13-19)27-22(14-23(28)15-24(18)27)10-11-25(31)29-35(32,33)26-7-4-12-34-26/h2-9,12-16H,10-11,17H2,1H3,(H,29,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50303678 (CHEMBL585100 | Thiophene-2-sulfonic acid [3-(5-flu...) Show SMILES Cc1cn(Cc2ccc3ccccc3c2)c2c(CCC(=O)NS(=O)(=O)c3cccs3)cc(F)cc12 Show InChI InChI=1S/C27H23FN2O3S2/c1-18-16-30(17-19-8-9-20-5-2-3-6-21(20)13-19)27-22(14-23(28)15-24(18)27)10-11-25(31)29-35(32,33)26-7-4-12-34-26/h2-9,12-16H,10-11,17H2,1H3,(H,29,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serum				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair