BDBM50303690 CHEMBL566015::Thiophene-2-sulfonic Acid[(E)-3-(1-Benzo[1,3]dioxol-5-ylmethyl-1H-indol-7-yl)acryloyl]amide

SMILES: O=C(NS(=O)(=O)c1cccs1)\C=C\c1cccc2ccn(Cc3ccc4OCOc4c3)c12

InChI Key: InChIKey=DKRMVIMIBYWMCW-VQHVLOKHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50303690 (CHEMBL566015 | Thiophene-2-sulfonic Acid[(E)-3-(1-...) Show SMILES O=C(NS(=O)(=O)c1cccs1)\C=C\c1cccc2ccn(Cc3ccc4OCOc4c3)c12 Show InChI InChI=1S/C23H18N2O5S2/c26-21(24-32(27,28)22-5-2-12-31-22)9-7-17-3-1-4-18-10-11-25(23(17)18)14-16-6-8-19-20(13-16)30-15-29-19/h1-13H,14-15H2,(H,24,26)/b9-7+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50303690 (CHEMBL566015 | Thiophene-2-sulfonic Acid[(E)-3-(1-...) Show SMILES O=C(NS(=O)(=O)c1cccs1)\C=C\c1cccc2ccn(Cc3ccc4OCOc4c3)c12 Show InChI InChI=1S/C23H18N2O5S2/c26-21(24-32(27,28)22-5-2-12-31-22)9-7-17-3-1-4-18-10-11-25(23(17)18)14-16-6-8-19-20(13-16)30-15-29-19/h1-13H,14-15H2,(H,24,26)/b9-7+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serum				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair