BDBM50303707 3,5-Difluoro-N-[(E)-3-(5-fluoro-1-imidazo[1,2-a]pyridin-2-ylmethyl-3-methyl-1H-indol-7-yl)acryloyl]benzenesulfonamide::CHEMBL566429

SMILES: Cc1cn(Cc2cn3ccccc3n2)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(F)cc(F)c3)cc(F)cc12

InChI Key: InChIKey=DBKCFFQIWNFRMN-AATRIKPKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303707   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50303707 (3,5-Difluoro-N-[(E)-3-(5-fluoro-1-imidazo[1,2-a]py...) Show SMILES Cc1cn(Cc2cn3ccccc3n2)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(F)cc(F)c3)cc(F)cc12 Show InChI InChI=1S/C26H19F3N4O3S/c1-16-13-33(15-21-14-32-7-3-2-4-24(32)30-21)26-17(8-18(27)12-23(16)26)5-6-25(34)31-37(35,36)22-10-19(28)9-20(29)11-22/h2-14H,15H2,1H3,(H,31,34)/b6-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50303707 (3,5-Difluoro-N-[(E)-3-(5-fluoro-1-imidazo[1,2-a]py...) Show SMILES Cc1cn(Cc2cn3ccccc3n2)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(F)cc(F)c3)cc(F)cc12 Show InChI InChI=1S/C26H19F3N4O3S/c1-16-13-33(15-21-14-32-7-3-2-4-24(32)30-21)26-17(8-18(27)12-23(16)26)5-6-25(34)31-37(35,36)22-10-19(28)9-20(29)11-22/h2-14H,15H2,1H3,(H,31,34)/b6-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serum				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair