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BDBM50303707 3,5-Difluoro-N-[(E)-3-(5-fluoro-1-imidazo[1,2-a]pyridin-2-ylmethyl-3-methyl-1H-indol-7-yl)acryloyl]benzenesulfonamide::CHEMBL566429

SMILES: Cc1cn(Cc2cn3ccccc3n2)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(F)cc(F)c3)cc(F)cc12

InChI Key: InChIKey=DBKCFFQIWNFRMN-AATRIKPKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303707   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50303707
PNG
(3,5-Difluoro-N-[(E)-3-(5-fluoro-1-imidazo[1,2-a]py...)
Show SMILES Cc1cn(Cc2cn3ccccc3n2)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(F)cc(F)c3)cc(F)cc12
Show InChI InChI=1S/C26H19F3N4O3S/c1-16-13-33(15-21-14-32-7-3-2-4-24(32)30-21)26-17(8-18(27)12-23(16)26)5-6-25(34)31-37(35,36)22-10-19(28)9-20(29)11-22/h2-14H,15H2,1H3,(H,31,34)/b6-5+
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.60n/an/an/an/an/an/a



deCODE Chemistry, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting


J Med Chem 53: 18-36 (2010)


Article DOI: 10.1021/jm9005912
BindingDB Entry DOI: 10.7270/Q2XP752H
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50303707
PNG
(3,5-Difluoro-N-[(E)-3-(5-fluoro-1-imidazo[1,2-a]py...)
Show SMILES Cc1cn(Cc2cn3ccccc3n2)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(F)cc(F)c3)cc(F)cc12
Show InChI InChI=1S/C26H19F3N4O3S/c1-16-13-33(15-21-14-32-7-3-2-4-24(32)30-21)26-17(8-18(27)12-23(16)26)5-6-25(34)31-37(35,36)22-10-19(28)9-20(29)11-22/h2-14H,15H2,1H3,(H,31,34)/b6-5+
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.05E+3n/an/an/an/an/an/a



deCODE Chemistry, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serum


J Med Chem 53: 18-36 (2010)


Article DOI: 10.1021/jm9005912
BindingDB Entry DOI: 10.7270/Q2XP752H
More data for this
Ligand-Target Pair