BDBM50303805 2-(4-(4-(4-(4-aminophenethylamino)-6-(3-aminophenylamino)-1,3,5-triazin-2-ylamino)phenethylamino)-6-(3-aminophenylamino)-1,3,5-triazin-2-ylamino)ethanol::CHEMBL570394

SMILES: Nc1ccc(CCNc2nc(Nc3ccc(CCNc4nc(NCCO)nc(Nc5cccc(N)c5)n4)cc3)nc(Nc3cccc(N)c3)n2)cc1

InChI Key: InChIKey=CRWAVDCABCBQJR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity immunoglobulin gamma Fc receptor I (Homo sapiens (Human))	BDBM50303805 (2-(4-(4-(4-(4-aminophenethylamino)-6-(3-aminopheny...) Show SMILES Nc1ccc(CCNc2nc(Nc3ccc(CCNc4nc(NCCO)nc(Nc5cccc(N)c5)n4)cc3)nc(Nc3cccc(N)c3)n2)cc1 Show InChI InChI=1S/C36H41N15O/c37-25-11-7-23(8-12-25)15-17-41-32-48-34(51-36(49-32)45-30-6-2-4-27(39)22-30)43-28-13-9-24(10-14-28)16-18-40-31-46-33(42-19-20-52)50-35(47-31)44-29-5-1-3-26(38)21-29/h1-14,21-22,52H,15-20,37-39H2,(H3,40,42,44,46,47,50)(H3,41,43,45,48,49,51)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
ProMetic BioSciences Inc. Curated by ChEMBL					Assay Description Inhibition of heat aggregated human IgG binding to human Fc-gamma-R1				J Med Chem 53: 1138-45 (2010) Checked by Author Article DOI: 10.1021/jm901403r BindingDB Entry DOI: 10.7270/Q21G0MC4
					More data for this Ligand-Target Pair
Low affinity immunoglobulin gamma Fc region receptor III-B (Homo sapiens (Human))	BDBM50303805 (2-(4-(4-(4-(4-aminophenethylamino)-6-(3-aminopheny...) Show SMILES Nc1ccc(CCNc2nc(Nc3ccc(CCNc4nc(NCCO)nc(Nc5cccc(N)c5)n4)cc3)nc(Nc3cccc(N)c3)n2)cc1 Show InChI InChI=1S/C36H41N15O/c37-25-11-7-23(8-12-25)15-17-41-32-48-34(51-36(49-32)45-30-6-2-4-27(39)22-30)43-28-13-9-24(10-14-28)16-18-40-31-46-33(42-19-20-52)50-35(47-31)44-29-5-1-3-26(38)21-29/h1-14,21-22,52H,15-20,37-39H2,(H3,40,42,44,46,47,50)(H3,41,43,45,48,49,51)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
ProMetic BioSciences Inc. Curated by ChEMBL					Assay Description Inhibition of heat aggregated human IgG binding to human Fc-gamma-R3b				J Med Chem 53: 1138-45 (2010) Checked by Author Article DOI: 10.1021/jm901403r BindingDB Entry DOI: 10.7270/Q21G0MC4
					More data for this Ligand-Target Pair
Low affinity immunoglobulin gamma Fc region receptor II-a (Homo sapiens (Human))	BDBM50303805 (2-(4-(4-(4-(4-aminophenethylamino)-6-(3-aminopheny...) Show SMILES Nc1ccc(CCNc2nc(Nc3ccc(CCNc4nc(NCCO)nc(Nc5cccc(N)c5)n4)cc3)nc(Nc3cccc(N)c3)n2)cc1 Show InChI InChI=1S/C36H41N15O/c37-25-11-7-23(8-12-25)15-17-41-32-48-34(51-36(49-32)45-30-6-2-4-27(39)22-30)43-28-13-9-24(10-14-28)16-18-40-31-46-33(42-19-20-52)50-35(47-31)44-29-5-1-3-26(38)21-29/h1-14,21-22,52H,15-20,37-39H2,(H3,40,42,44,46,47,50)(H3,41,43,45,48,49,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
ProMetic BioSciences Inc. Curated by ChEMBL					Assay Description Inhibition of heat aggregated human IgG binding to human Fc-gamma-R2a				J Med Chem 53: 1138-45 (2010) Checked by Author Article DOI: 10.1021/jm901403r BindingDB Entry DOI: 10.7270/Q21G0MC4
					More data for this Ligand-Target Pair