null

SMILES: CN1CCN(CC1)c1cccc2[nH]c(Cc3cccc4ccccc34)nc12

InChI Key: InChIKey=DZCOFFSCUNYLGZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50304000 (4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...) Show SMILES CN1CCN(CC1)c1cccc2[nH]c(Cc3cccc4ccccc34)nc12 Show InChI InChI=1S/C23H24N4/c1-26-12-14-27(15-13-26)21-11-5-10-20-23(21)25-22(24-20)16-18-8-4-7-17-6-2-3-9-19(17)18/h2-11H,12-16H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50304000 (4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...) Show SMILES CN1CCN(CC1)c1cccc2[nH]c(Cc3cccc4ccccc34)nc12 Show InChI InChI=1S/C23H24N4/c1-26-12-14-27(15-13-26)21-11-5-10-20-23(21)25-22(24-20)16-18-8-4-7-17-6-2-3-9-19(17)18/h2-11H,12-16H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50304000 (4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...) Show SMILES CN1CCN(CC1)c1cccc2[nH]c(Cc3cccc4ccccc34)nc12 Show InChI InChI=1S/C23H24N4/c1-26-12-14-27(15-13-26)21-11-5-10-20-23(21)25-22(24-20)16-18-8-4-7-17-6-2-3-9-19(17)18/h2-11H,12-16H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair