BDBM50304114 CHEMBL445348::N-{(Z)-3-[(E)-Hydroxyimino]-2'-oxo-1,3,1',2'-tetrahydro-[2,3']biindolyliden-5'-yl}-acetamide::N-{3-[Hydroxyimino]-2'-oxo-1,3,1',2'-tetrahydro-[2,3']biindolyliden-5'-yl}-acetamide

SMILES: CC(=O)Nc1ccc2NC(=O)C(c2c1)c1[nH]c2ccccc2c1N=O

InChI Key: InChIKey=JGKMVFDNLDMZCI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50304114 (CHEMBL445348 | N-{(Z)-3-[(E)-Hydroxyimino]-2'-oxo-...) Show SMILES CC(=O)Nc1ccc2NC(=O)C(c2c1)c1[nH]c2ccccc2c1N=O Show InChI InChI=1S/C18H14N4O3/c1-9(23)19-10-6-7-14-12(8-10)15(18(24)21-14)17-16(22-25)11-4-2-3-5-13(11)20-17/h2-8,15,20H,1H3,(H,19,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de La Rochelle Curated by ChEMBL					Assay Description Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation counting				Bioorg Med Chem 17: 6257-63 (2009) Article DOI: 10.1016/j.bmc.2009.07.051 BindingDB Entry DOI: 10.7270/Q2BR8S9W
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (RAT)	BDBM50304114 (CHEMBL445348 | N-{(Z)-3-[(E)-Hydroxyimino]-2'-oxo-...) Show SMILES CC(=O)Nc1ccc2NC(=O)C(c2c1)c1[nH]c2ccccc2c1N=O Show InChI InChI=1S/C18H14N4O3/c1-9(23)19-10-6-7-14-12(8-10)15(18(24)21-14)17-16(22-25)11-4-2-3-5-13(11)20-17/h2-8,15,20H,1H3,(H,19,23)(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de La Rochelle Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...				Bioorg Med Chem 17: 6257-63 (2009) Article DOI: 10.1016/j.bmc.2009.07.051 BindingDB Entry DOI: 10.7270/Q2BR8S9W
					More data for this Ligand-Target Pair