BDBM50304153 3-(2-Furyl)-2-(N-methylthiocarbamoyl)-3,3a,4,5,6,7-hexahydro-2H-indazol::CHEMBL607552
SMILES: CNC(=S)N1N=C2CCCCC2C1c1ccco1
InChI Key: InChIKey=FBNZNYMVFHXNOR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat)) | BDBM50304153 (3-(2-Furyl)-2-(N-methylthiocarbamoyl)-3,3a,4,5,6,7...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University Curated by ChEMBL | Assay Description Competitive inhibition of MAOB in rat liver homogenate by spectrophotometrically | Bioorg Med Chem 17: 6761-72 (2009) Article DOI: 10.1016/j.bmc.2009.07.033 BindingDB Entry DOI: 10.7270/Q2TQ61M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine oxidase (Rattus norvegicus (rat)) | BDBM50304153 (3-(2-Furyl)-2-(N-methylthiocarbamoyl)-3,3a,4,5,6,7...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University Curated by ChEMBL | Assay Description Competitive inhibition of MAOA in rat liver homogenate by spectrophotometrically | Bioorg Med Chem 17: 6761-72 (2009) Article DOI: 10.1016/j.bmc.2009.07.033 BindingDB Entry DOI: 10.7270/Q2TQ61M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat)) | BDBM50304153 (3-(2-Furyl)-2-(N-methylthiocarbamoyl)-3,3a,4,5,6,7...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University Curated by ChEMBL | Assay Description Competitive inhibition of MAOB in rat liver homogenate by spectrophotometrically | Bioorg Med Chem 17: 6761-72 (2009) Article DOI: 10.1016/j.bmc.2009.07.033 BindingDB Entry DOI: 10.7270/Q2TQ61M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine oxidase (Rattus norvegicus (rat)) | BDBM50304153 (3-(2-Furyl)-2-(N-methylthiocarbamoyl)-3,3a,4,5,6,7...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.08E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University Curated by ChEMBL | Assay Description Competitive inhibition of MAOA in rat liver homogenate by spectrophotometrically | Bioorg Med Chem 17: 6761-72 (2009) Article DOI: 10.1016/j.bmc.2009.07.033 BindingDB Entry DOI: 10.7270/Q2TQ61M2 | |||||||||||
More data for this Ligand-Target Pair |