BDBM50304268 (S)-2-(1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pyrrolidin-2-yl)acetic acid::CHEMBL603863
SMILES: [#6]-c1ccsc1\[#6](=[#6]/[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6]-[#6](-[#8])=O)-c1sccc1-[#6]
InChI Key: InChIKey=YVXKVESMVWOZMB-INIZCTEOSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GABA transporter (Mus musculus) | BDBM50304268 ((S)-2-(1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Microbiology Curated by ChEMBL | Assay Description Inhibition of GAT3 in mouse D8 cells assessed as [3H]GABA transport by liquid scintillation counting | Bioorg Med Chem 17: 6540-6 (2009) Article DOI: 10.1016/j.bmc.2009.08.010 BindingDB Entry DOI: 10.7270/Q26110DK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA transporter (Mus musculus) | BDBM50304268 ((S)-2-(1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Microbiology Curated by ChEMBL | Assay Description Inhibition of GAT1 in mouse D8 cells assessed as [3H]GABA transport by liquid scintillation counting | Bioorg Med Chem 17: 6540-6 (2009) Article DOI: 10.1016/j.bmc.2009.08.010 BindingDB Entry DOI: 10.7270/Q26110DK | |||||||||||
More data for this Ligand-Target Pair |