BDBM50304588 (R,S)-N-[2-Benzoyl-4-(3-phenylpropionyl)aminophenyl]-2-(4-methylpiperazin-1-yl)-2-phenylacetamide::CHEMBL595713

SMILES: CN1CCN(CC1)C(C(=O)Nc1ccc(NC(=O)CCc2ccccc2)cc1C(=O)c1ccccc1)c1ccccc1

InChI Key: InChIKey=POMIGTJNLSPLAH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304588   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-glycoprotein 1 (Homo sapiens (Human))	BDBM50304588 ((R,S)-N-[2-Benzoyl-4-(3-phenylpropionyl)aminopheny...) Show SMILES CN1CCN(CC1)C(C(=O)Nc1ccc(NC(=O)CCc2ccccc2)cc1C(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H36N4O3/c1-38-21-23-39(24-22-38)33(27-13-7-3-8-14-27)35(42)37-31-19-18-29(25-30(31)34(41)28-15-9-4-10-16-28)36-32(40)20-17-26-11-5-2-6-12-26/h2-16,18-19,25,33H,17,20-24H2,1H3,(H,36,40)(H,37,42)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Inhibition of ABCB1 overexpressed in human CCRF-CEM/VCR1000 cell assessed as inhibition of daunomycin efflux after 30 mins by FACS analysis				Bioorg Med Chem 17: 7690-7 (2009) Article DOI: 10.1016/j.bmc.2009.09.043 BindingDB Entry DOI: 10.7270/Q2319W02
					More data for this Ligand-Target Pair