BDBM50304611 3-(5-((5-(4-chlorophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid::CHEMBL593602

SMILES: OC(=O)CCN1C(=S)S\C(=C\c2ccc(o2)-c2ccc(Cl)cc2)C1=O

InChI Key: InChIKey=YZLFZFALAZYTCI-NTEUORMPSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1 (FIH) (Homo sapiens (Human))	BDBM50304611 (3-(5-((5-(4-chlorophenyl)furan-2-yl)methylene)-4-o...) Show SMILES OC(=O)CCN1C(=S)S\C(=C\c2ccc(o2)-c2ccc(Cl)cc2)C1=O Show InChI InChI=1S/C17H12ClNO4S2/c18-11-3-1-10(2-4-11)13-6-5-12(23-13)9-14-16(22)19(17(24)25-14)8-7-15(20)21/h1-6,9H,7-8H2,(H,20,21)/b14-9+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sejong University Curated by ChEMBL					Assay Description Inhibition of human recombinant FIH1				Bioorg Med Chem 17: 7769-74 (2009) Article DOI: 10.1016/j.bmc.2009.09.034 BindingDB Entry DOI: 10.7270/Q2TM7B6R
					More data for this Ligand-Target Pair