BDBM50304740 2-(3-(1-Carboxy-2-(4-hydroxy-3-iodophenyl)ethyl)ureido)-4-methylpentanoic acid::CHEMBL611355

SMILES: CC(C)C[C@H](NC(=O)N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O)C(O)=O

InChI Key: InChIKey=XZRCMEYKRXIALC-RYUDHWBXSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate carboxypeptidase II (Homo sapiens (Human))	BDBM50304740 (2-(3-(1-Carboxy-2-(4-hydroxy-3-iodophenyl)ethyl)ur...) Show SMILES CC(C)C[C@H](NC(=O)N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C16H21IN2O6/c1-8(2)5-11(14(21)22)18-16(25)19-12(15(23)24)7-9-3-4-13(20)10(17)6-9/h3-4,6,8,11-12,20H,5,7H2,1-2H3,(H,21,22)(H,23,24)(H2,18,19,25)/t11-,12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institutions Curated by ChEMBL					Assay Description Inhibition of glutamate carboxypeptidase 2 in human LNCaP cells by fluorescence based NAALADase assay				Bioorg Med Chem Lett 20: 392-7 (2010) Article DOI: 10.1016/j.bmcl.2009.10.061 BindingDB Entry DOI: 10.7270/Q2SN092X
					More data for this Ligand-Target Pair