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SMILES: COC(=O)[C@H](CC(C)C)NC(=O)N[C@@H](CCc1c[nH]c2ccccc12)C(O)=O

InChI Key: InChIKey=DYCBJYJYSYEDMD-IRXDYDNUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304747   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate carboxypeptidase 2


(Homo sapiens (Human))		BDBM50304747
PNG
((S)-2-(3-((S)-1-Carboxy-2-(1H-indol-3-yl)ethyl)ure...)
Show SMILES COC(=O)[C@H](CC(C)C)NC(=O)N[C@@H](CCc1c[nH]c2ccccc12)C(O)=O |r|
Show InChI InChI=1S/C20H27N3O5/c1-12(2)10-17(19(26)28-3)23-20(27)22-16(18(24)25)9-8-13-11-21-15-7-5-4-6-14(13)15/h4-7,11-12,16-17,21H,8-10H2,1-3H3,(H,24,25)(H2,22,23,27)/t16-,17-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+6n/an/an/an/an/an/an/an/a



Institutions

Curated by ChEMBL


Assay Description
Inhibition of glutamate carboxypeptidase 2 in human LNCaP cells by fluorescence based NAALADase assay

Bioorg Med Chem Lett 20: 392-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.061
BindingDB Entry DOI: 10.7270/Q2SN092X
More data for this
Ligand-Target Pair