BDBM50304749 (S)-2-(3-(3-Carboxypropyl)ureido)-6-(4-iodobenzamido)hexanoic acid::CHEMBL608106
SMILES: OC(=O)CCCNC(=O)N[C@@H](CCCCNC(=O)c1ccc(I)cc1)C(O)=O
InChI Key: InChIKey=MCRUGHVJVJAFST-AWEZNQCLSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate carboxypeptidase II (Homo sapiens (Human)) | BDBM50304749 ((S)-2-(3-(3-Carboxypropyl)ureido)-6-(4-iodobenzami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institutions Curated by ChEMBL | Assay Description Inhibition of human cloned glutamate carboxypeptidase 2 | Bioorg Med Chem Lett 20: 392-7 (2010) Article DOI: 10.1016/j.bmcl.2009.10.061 BindingDB Entry DOI: 10.7270/Q2SN092X | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |