BDBM50304752 3-(4-tert-Butylphenyl)-N-[3-fluoro-4-(methylsulfonamido)benzyl]propanethioamide::CHEMBL596537
SMILES: CC(C)(C)c1ccc(CCC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1
InChI Key: InChIKey=UTJFIPFNFXVPDK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vanilloid receptor (Rattus norvegicus (rat)) | BDBM50304752 (3-(4-tert-Butylphenyl)-N-[3-fluoro-4-(methylsulfon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neurons assessed as inhibition of capsaicin-induced [45]Ca2+ uptake | Bioorg Med Chem 17: 8149-60 (2009) Article DOI: 10.1016/j.bmc.2009.10.043 BindingDB Entry DOI: 10.7270/Q2NV9JBN | |||||||||||
More data for this Ligand-Target Pair |