BDBM50304777 2-(4-(7-hydroxy-2,3-dihydro-1H-inden-4-yloxy)-3,5-dimethylphenylamino)-2-oxoacetic acid::CHEMBL608990

SMILES: Cc1cc(NC(=O)C(O)=O)cc(C)c1Oc1ccc(O)c2CCCc12

InChI Key: InChIKey=CEYPDXWCYTVSDN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50304777 (2-(4-(7-hydroxy-2,3-dihydro-1H-inden-4-yloxy)-3,5-...) Show SMILES Cc1cc(NC(=O)C(O)=O)cc(C)c1Oc1ccc(O)c2CCCc12 Show InChI InChI=1S/C19H19NO5/c1-10-8-12(20-18(22)19(23)24)9-11(2)17(10)25-16-7-6-15(21)13-4-3-5-14(13)16/h6-9,21H,3-5H2,1-2H3,(H,20,22)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Binding affinity to thyroid receptor beta				Bioorg Med Chem Lett 20: 306-8 (2010) Article DOI: 10.1016/j.bmcl.2009.10.109 BindingDB Entry DOI: 10.7270/Q2J38SNP
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50304777 (2-(4-(7-hydroxy-2,3-dihydro-1H-inden-4-yloxy)-3,5-...) Show SMILES Cc1cc(NC(=O)C(O)=O)cc(C)c1Oc1ccc(O)c2CCCc12 Show InChI InChI=1S/C19H19NO5/c1-10-8-12(20-18(22)19(23)24)9-11(2)17(10)25-16-7-6-15(21)13-4-3-5-14(13)16/h6-9,21H,3-5H2,1-2H3,(H,20,22)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Binding affinity to thyroid receptor alpha				Bioorg Med Chem Lett 20: 306-8 (2010) Article DOI: 10.1016/j.bmcl.2009.10.109 BindingDB Entry DOI: 10.7270/Q2J38SNP
					More data for this Ligand-Target Pair