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SMILES: Clc1cccc(COc2nc(nc3nc[nH]c23)N2CCNCC2)c1

InChI Key: InChIKey=AOILUVBUHWCWKN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304822   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50304822
PNG
(6-(3-chlorobenzyloxy)-2-(piperazin-1-yl)-9H-purine...)
Show SMILES Clc1cccc(COc2nc(nc3nc[nH]c23)N2CCNCC2)c1
Show InChI InChI=1S/C16H17ClN6O/c17-12-3-1-2-11(8-12)9-24-15-13-14(20-10-19-13)21-16(22-15)23-6-4-18-5-7-23/h1-3,8,10,18H,4-7,9H2,(H,19,20,21,22)
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n/an/a 410n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity against human 5HT2C receptor by FLIPR assay

Bioorg Med Chem Lett 20: 266-71 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.112
BindingDB Entry DOI: 10.7270/Q2154H5M
More data for this
Ligand-Target Pair