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BDBM50304843 4-(4-hydroxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one::CHEMBL603423

SMILES: Cn1c(c(-c2ccc(O)cc2)c(=O)n1C)-c1ccc2nccnc2c1

InChI Key: InChIKey=VNQDUOVTNODMKN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304843   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50304843
PNG
(4-(4-hydroxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-y...)
Show SMILES Cn1c(c(-c2ccc(O)cc2)c(=O)n1C)-c1ccc2nccnc2c1
Show InChI InChI=1S/C19H16N4O2/c1-22-18(13-5-8-15-16(11-13)21-10-9-20-15)17(19(25)23(22)2)12-3-6-14(24)7-4-12/h3-11,24H,1-2H3
PDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
9.50E+5n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation counting


Bioorg Med Chem Lett 20: 326-9 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.108
BindingDB Entry DOI: 10.7270/Q2RN37ZK
More data for this
Ligand-Target Pair