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SMILES: Nc1nccc(Nc2ccc3[nH]nc(-c4ccsc4)c3c2)n1

InChI Key: InChIKey=HGKSWPMTSBTIJQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304998   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (Human))		BDBM50304998
PNG
(CHEMBL589626 | N4-(3-(thiophen-3-yl)-1H-indazol-5-...)
Show SMILES Nc1nccc(Nc2ccc3[nH]nc(-c4ccsc4)c3c2)n1
Show InChI InChI=1S/C15H12N6S/c16-15-17-5-3-13(19-15)18-10-1-2-12-11(7-10)14(21-20-12)9-4-6-22-8-9/h1-8H,(H,20,21)(H3,16,17,18,19)
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n/an/a 3.40E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of MK2

Bioorg Med Chem Lett 20: 334-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.103
BindingDB Entry DOI: 10.7270/Q2VD6ZJJ
More data for this
Ligand-Target Pair