BDBM50305004 7-(1H-indazol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine::CHEMBL584640

SMILES: Nc1ncc2ccn(-c3ccc4[nH]ncc4c3)c2n1

InChI Key: InChIKey=ZSWJIMAKJQWETI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50305004 (7-(1H-indazol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-a...) Show SMILES Nc1ncc2ccn(-c3ccc4[nH]ncc4c3)c2n1 Show InChI InChI=1S/C13H10N6/c14-13-15-6-8-3-4-19(12(8)17-13)10-1-2-11-9(5-10)7-16-18-11/h1-7H,(H,16,18)(H2,14,15,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 20: 334-7 (2010) Article DOI: 10.1016/j.bmcl.2009.10.103 BindingDB Entry DOI: 10.7270/Q2VD6ZJJ
					More data for this Ligand-Target Pair