BDBM50305017 (6-(4-chlorophenylamino)pyridin-3-yl)(piperidin-1-yl)methanone::CHEMBL595943

SMILES: Clc1ccc(Nc2ccc(cn2)C(=O)N2CCCCC2)cc1

InChI Key: InChIKey=AGWSNYOZTIPZLY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305017   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50305017 ((6-(4-chlorophenylamino)pyridin-3-yl)(piperidin-1-...) Show SMILES Clc1ccc(Nc2ccc(cn2)C(=O)N2CCCCC2)cc1 Show InChI InChI=1S/C17H18ClN3O/c18-14-5-7-15(8-6-14)20-16-9-4-13(12-19-16)17(22)21-10-2-1-3-11-21/h4-9,12H,1-3,10-11H2,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 assessed as inhibition of glutamate-induced elevation of intracellular calcium concentration				Bioorg Med Chem Lett 20: 184-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.001 BindingDB Entry DOI: 10.7270/Q2QN66VN
					More data for this Ligand-Target Pair