null
SMILES: COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)[C@]1(OC)C=C[C@@]35C[C@@H]1c1ccccc1
InChI Key: InChIKey=QMPVAJYKJRMMQD-FGYBOQAASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50305084 (7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Displacement of [3H]diprenorphine from human kappa receptor expressed in CHO cells by scintillation counting | Bioorg Med Chem Lett 20: 418-21 (2010) Article DOI: 10.1016/j.bmcl.2009.07.119 BindingDB Entry DOI: 10.7270/Q2BG2P4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50305084 (7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Displacement of [3H]diprenorphine from rat mu receptor expressed in CHO cells by scintillation counting | Bioorg Med Chem Lett 20: 418-21 (2010) Article DOI: 10.1016/j.bmcl.2009.07.119 BindingDB Entry DOI: 10.7270/Q2BG2P4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50305084 (7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Displacement of [3H]diprenorphine from rat delta receptor expressed in CHO cells by scintillation counting | Bioorg Med Chem Lett 20: 418-21 (2010) Article DOI: 10.1016/j.bmcl.2009.07.119 BindingDB Entry DOI: 10.7270/Q2BG2P4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50305084 (7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Agonist activity at rat mu opioid receptor assessed as stimulation of [35]SGTPgammaS binding | Bioorg Med Chem Lett 20: 418-21 (2010) Article DOI: 10.1016/j.bmcl.2009.07.119 BindingDB Entry DOI: 10.7270/Q2BG2P4C | |||||||||||
More data for this Ligand-Target Pair |