null

SMILES: CCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2c(F)cc3CCNC(=O)c3c2C1

InChI Key: InChIKey=BNXCKNFYLODKCG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50305091 ((+/-)-9-(ethyl(3-(5-fluoro-1H-indol-3-yl)propyl)am...) Show SMILES CCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2c(F)cc3CCNC(=O)c3c2C1 Show InChI InChI=1S/C25H27F2N3O2/c1-2-30(9-3-4-16-13-29-22-6-5-17(26)11-19(16)22)18-12-20-23-15(7-8-28-25(23)31)10-21(27)24(20)32-14-18/h5-6,10-11,13,18,29H,2-4,7-9,12,14H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]OH-DPAP from human 5HT1A receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 222-7 (2010) Article DOI: 10.1016/j.bmcl.2009.10.134 BindingDB Entry DOI: 10.7270/Q26Q1XC6
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50305091 ((+/-)-9-(ethyl(3-(5-fluoro-1H-indol-3-yl)propyl)am...) Show SMILES CCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2c(F)cc3CCNC(=O)c3c2C1 Show InChI InChI=1S/C25H27F2N3O2/c1-2-30(9-3-4-16-13-29-22-6-5-17(26)11-19(16)22)18-12-20-23-15(7-8-28-25(23)31)10-21(27)24(20)32-14-18/h5-6,10-11,13,18,29H,2-4,7-9,12,14H2,1H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of labeled paroxetine from 5-HT transporter				Bioorg Med Chem Lett 20: 222-7 (2010) Article DOI: 10.1016/j.bmcl.2009.10.134 BindingDB Entry DOI: 10.7270/Q26Q1XC6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50305091 ((+/-)-9-(ethyl(3-(5-fluoro-1H-indol-3-yl)propyl)am...) Show SMILES CCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2c(F)cc3CCNC(=O)c3c2C1 Show InChI InChI=1S/C25H27F2N3O2/c1-2-30(9-3-4-16-13-29-22-6-5-17(26)11-19(16)22)18-12-20-23-15(7-8-28-25(23)31)10-21(27)24(20)32-14-18/h5-6,10-11,13,18,29H,2-4,7-9,12,14H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human 5HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-induced adenylate cyclase activity				Bioorg Med Chem Lett 20: 222-7 (2010) Article DOI: 10.1016/j.bmcl.2009.10.134 BindingDB Entry DOI: 10.7270/Q26Q1XC6
					More data for this Ligand-Target Pair