BDBM50305118 7-(2-(4-methylpiperazin-1-yl)ethoxy)-2-(4-phenoxyphenyl)-9,10-dihydro-4H-benzo[d]pyrazolo[1,5-a][1,3]diazepine-3-carboxamide::CHEMBL603859

SMILES: CN1CCN(CCOc2ccc3Nc4c(C(N)=O)c(nn4CCc3c2)-c2ccc(Oc3ccccc3)cc2)CC1

InChI Key: InChIKey=XNWLBELCPUAJCK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305118 (7-(2-(4-methylpiperazin-1-yl)ethoxy)-2-(4-phenoxyp...) Show SMILES CN1CCN(CCOc2ccc3Nc4c(C(N)=O)c(nn4CCc3c2)-c2ccc(Oc3ccccc3)cc2)CC1 Show InChI InChI=1S/C31H34N6O3/c1-35-15-17-36(18-16-35)19-20-39-26-11-12-27-23(21-26)13-14-37-31(33-27)28(30(32)38)29(34-37)22-7-9-25(10-8-22)40-24-5-3-2-4-6-24/h2-12,21,33H,13-20H2,1H3,(H2,32,38)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair