BDBM50305121 7-(2-(dimethylamino)ethoxy)-2-(4-(phenylamino)phenyl)-9,10-dihydro-4H-benzo[d]pyrazolo[1,5-a][1,3]diazepine-3-carboxamide::CHEMBL595624

SMILES: CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(Nc2ccccc2)cc1

InChI Key: InChIKey=HJOPCSCHXHRCGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305121 (7-(2-(dimethylamino)ethoxy)-2-(4-(phenylamino)phen...) Show SMILES CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(Nc2ccccc2)cc1 Show InChI InChI=1S/C28H30N6O2/c1-33(2)16-17-36-23-12-13-24-20(18-23)14-15-34-28(31-24)25(27(29)35)26(32-34)19-8-10-22(11-9-19)30-21-6-4-3-5-7-21/h3-13,18,30-31H,14-17H2,1-2H3,(H2,29,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair